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In Fincher's Mindhunter, Holden Ford, the character based on Douglas, is played by Jonathan Groff.

If David Fincher's Mindhunter feels a bit like Silence of the Lambs, that's because Douglas was the real-life inspiration for fictional FBI Special Agent Jack Crawford (Scott Glenn in that film), the protagonist in Thomas Harris's Hannibal Lecter novels. Douglas analyzed the behaviors of, among other serial killers, Jeffrey Dahmer and Ted Bundy. The FBI was wary of these methods at first, but came to adopt them in time. He was the first to come up with a psychological profile of the Unabomber. Douglas helped to pioneer the idea of profiling serious criminals-to think like a predator. Netflix's Mindhunter is loosely based on the non-fiction book Mindhunter by John Douglas, a former FBI agent, and Mark Olshaker, a writer and filmmaker.